The graphics tablet I use, works as expected with Gnome 3. I can use absolute positioning on my multi monitor setup. I've set one of my two monitors to be used with the graphics tables. This way, if you draw a circle, you actually get a circle.
On XFCE, the tablet works fine, but I can't set it to use just one monitor. This means, that on my multi monitor setup, it is quite unusable. If you draw a circle, you get a pretty squashed ellipse.
I haven't found a setting for that as of yet.
The tablet is a "Waltop A".