Is it possible to cause kernel panic by removing a device driver and then making a system call that uses that driver so that kernel goes in panic?
It is possible when driver is not properly removed and application tried to use. If driver is removed properly kernel will give error like driver not found but never crash(In 99.99% cases until it hit any bug).
It is highly possible on the environment where the OS is configured on the SAN (Storage Area Networks) disks.
In my current client all servers boot disks are configured/installed with the SAN disks, i have seen many times kernel panic when the device driver not loaded or it's deleted.