I am looking for a good book or online article on analysis and tuning Linux system performance.
So far I've found openSUSE 12.2 System Analysis and Tuning Guide which looks promising. Any other recommendations?
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Without delving into details of applications running on the system which is where normally performance tuning would start you can start looking at system performance through:
This list is by no means complete and by no means likely to give you answers on what you might be doing. Given that you are running multiple virtual machines I would first recommend analysis of applications running in those environments and whether or not virtualization is actually necessary.