I have a problem with the Arial font that I have installed together with Wine. It's causing a strange behavior while editing annotations in the Linux version of Foxit PDF Reader. If I remove this font, I then experience problems in the display of some websites (e.g. DistroWatch) under Firefox.
There is a very useful font replacement table in LibreOffice options for such purposes. So I wonder if there's a similar way doing this system-wide in Linux - e.g. telling the system and all apps to use say DejaVu Sans for Arial.