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I have a KVM virtual machine running CentOS 7 on a host running Fedora 24. I have a usb-serial dongle (actually a RFID reader but that should really not matter) that is installed on the host. The host can see it after running:

sudo modprobe usbserial vendor=0x1325 product=0xc02a

I have access to /dev/ttyACM0 which is the device I need to talk to.

How do I can access to said device on the guest (CentOS 7) system?

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As Cas suggested in a comment, you can use the virt-manager GUI to do that:

GUI

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