I performed an upgrade from fedora 21 to fedora 22 today. I used FedUp and followed the instructions at https://fedoraproject.org/wiki/FedUp
Afterwards I installed fedy and activated some tweaks (Codecs,Archive formats, Microsoft fonts, font rendering, SELinux permissive)
usbredir is still installed. In f21 I always used virt-manager for everything, because I am quite new to the Linux world.
I'm sure it should be a minor update related issue, but I can't figure out what went wrong. The VMs (ubuntu LTS and Win7_x64) both boot fine, but I can't add USB devices (The menu Virtual Machine -> Redirect USB is greyed out in virt-manager and Boxes gives a generic failure message).
I'm happy to share relevant terminal output. However, I don't know where to start.