I am running Debian Testing with LXDE.
After some time of work, some applications begin to show confused fonts, as shown in the following screenshot (the pdf specific area is good):

This happens with evince and with notification (sent from wicd, clementine, etc., I suppose through notify-send).
Cannot say what other applications show the problem, but almost all other applications work good, for example iceweasel (firefox), icedove (thunderbird), xchat, lxterminal, etc.
How to diagnose the problem?